What science measures in stones
Chemical composition, crystal structure, hardness, cleavage, density and optical properties are measurable features well described in the mineralogical literature — the cards’ “Mineralogy” and “How to identify” sections rest on them. The mere existence of measurable crystal properties, however, says nothing about effects on health or wellbeing: such a claim has to be tested separately, in a study with a suitable comparison group. [1]
Two controlled studies
The largest study we found was published in 2025 by Escolà-Gascón and colleagues. 138 adults were classified as believers or non-believers in crystals and randomly assigned to rose quartz or a visually similar placebo object for 14 days. Anxiety fell only among believers — whether or not they had real quartz — and no difference between the groups was shown. The authors attribute the change to expectation and conditioning. Participants did not have diagnosed anxiety disorders. [36]
The second study concerned amethyst: in a Danish double-blind study from 2025, 38 healthcare workers carried an amethyst or a similar stone for four weeks; neither group changed its lifestyle or self-rated health. It was a small study of healthy people, published in a light-hearted Christmas issue of a medical journal, with 18% drop-out. Both studies concern their own stones, duration and protocol. [126]
See in Avonoria: Rose quartz · Amethyst
How we searched the literature
On 4 October 2026 we searched PubMed for each of the 20 materials, combining the stone’s name with terms such as “crystal healing”, “lithotherapy”, “placebo”, “anxiety”, “meditation” or “wellbeing”. For 18 materials we found no studies of lithotherapy; most hits were chance name matches — drug trials with such acronyms, selenium chemistry, the dye malachite green, technical uses of tourmaline. We record the queries in our editorial documentation. No hits is the result of our search, not proof that no study exists. [129]
Two results needed separate explanation. A 2023 review concerned Chinese compound medicines containing pyrite used for fractures — an entirely different practice from lithotherapy and no reason to take pyrite oneself. Studies of facial rollers and gua sha massage compare massage techniques, not materials, so they say nothing about jadeite. [127] [128]
How to read these results
The rose-quartz study is not a test of sodalite or hematite, and the amethyst result says nothing about labradorite. That is why the cards do not transfer results from one stone to another: for stones nobody has studied we state plainly that we found no studies. Conversely, the absence of studies does not confirm the beliefs — it only means the question has not been tested. [36] [126] [129]
The 2025 study shows something important for practice: the improvement people felt was linked to their expectations, not to the kind of object in their hand. The authors note that context, attention and the therapeutic relationship can amplify such responses. This does not, however, justify attributing healing effects to stones or replacing treatment with them. [36]
How we write the “What science says” notes
Each note is one short paragraph and concerns only the material in question: if there is a study of that stone, we describe it; if not, we say what the results found were about. We do not repeat long disclaimers in every paragraph of the tradition description; this page is the place for the wider context. Real physical hazards — dust, composition, fire, swallowing — are described separately, in the safety section and in the mineral safety guide.
See in Avonoria: Mineral safety · Crystal atlas
What this means for someone who practises
Many people value working with stones as a ritual, a moment of focus, a connection with nature or the beauty of a collection — and that is a value independent of clinical trial results. For health problems, stones may accompany a practice, but they do not replace a doctor’s advice or treatment. This separation lets us write about lithotherapy respectfully and honestly at the same time.
See in Avonoria: What is lithotherapy? · Meditation and intention practice
Read next
What is lithotherapy?Mineral safetyMineral, crystal, rock and gemstoneMeditation and intention practiceCrystal atlas →Guide sources
- Quartz (external link, opens in a new tab)Mineral Data Publishing / Handbook of Mineralogy · accessed 2026-09-30
Mineralogical, gemological, institutional or scientific source. Its scope is recorded in the source index.
- Placebo effects in alternative medical treatments for anxiety: false hope or healing potential? (external link, opens in a new tab)Cambridge University Press / CNS Spectrums · 2025 · accessed 2026-09-30DOI: 10.1017/S1092852925100515
Mineralogical, gemological, institutional or scientific source. Its scope is recorded in the source index.
- Christmas article: Crystal clear result: No effect of amethyst on KRAM-S factors and health after Christmas (external link, opens in a new tab)Ugeskrift for Læger · 2025 · accessed 2026-10-04DOI: 10.61409/V20254
Mineralogical, gemological, institutional or scientific source. Its scope is recorded in the source index.
- PubMed searches for crystal names with lithotherapy/placebo/anxiety/meditation terms (external link, opens in a new tab)U.S. National Library of Medicine — PubMed (E-utilities) · 2026 · accessed 2026-10-04
Record of a literature-database search: no hits does not prove that no study exists.
- Therapeutic Efficacy of Chinese Patent Medicine Containing Pyrite for Fractures: A Systematic Review and Meta-Analysis (external link, opens in a new tab)Medicina (Kaunas) · 2023 · accessed 2026-10-04DOI: 10.3390/medicina60010076
Mineralogical, gemological, institutional or scientific source. Its scope is recorded in the source index.
- Comparative Effects of Facial Roller and Gua Sha Massage on Facial Contour, Muscle Tone, and Skin Elasticity: Randomized Controlled Trial (external link, opens in a new tab)Journal of Cosmetic Dermatology · 2025 · accessed 2026-10-04DOI: 10.1111/jocd.70236
Mineralogical, gemological, institutional or scientific source. Its scope is recorded in the source index.